Insights

2013 “Chirally deuterated benzyl chlorides from benzyl alcohols via hexachloroacetone/polymer-supported triphenylphosphine: synthesis of protected (2S,3S)-[3-2H,15N]-tyrosine” J Labelled Comp Radiopharm, 56: 6‑11 Derek Barnett, Ph.D.

Issued June 23, 2009 U.S. Patent No. 7,550,510 (Curley et al. – The Ohio State University Research Foundation) entitled "Solid Phase Synthesis of Arylretinamides" Derek Barnett, Ph.D.

2007 "The unhydrolyzable fenretinide, 4-HBR, induces the proapoptotic genes GADD153 (CHOP) and BBC3 (PUMA) and apoptosis that is caspase-dependent and independent of the retinoic acid receptor” Cancer Research, 67: 6270-6277 Derek Barnett, Ph.D.

2002 "Photo/affinity label analogs of N-(4-hydroxyphenyl)retinamide” 224th National Meeting of the American Chemical Society, Boston, MA, MEDI 143 Derek Barnett, Ph.D.

2002 "Isotopically labeled amino acids: stereochemical implications of hexachloroacetone/polymer supported triphenylphosphine chlorination of chirally deuterated benzylic alcohols” 224th National Meeting of the American Chemical Society, Boston, MA, MEDI 404 Derek Barnett, Ph.D.

2002 "Stereoselective route to 15N-labeled-β-deuterated amino acids: synthesis of (2S,3R)-3-2H,15N]-phenylalanine” Tetrahedron: Asymmetry, 13: 1893-1900 Derek Barnett, Ph.D.

1999 "Synthetic efforts toward the stereoselective synthesis of β-deuterated amino acids for studies of protein structure by multidimensional NMR" 36th National Organic Chemistry Symposium, Madison, WI Derek Barnett, Ph.D.

1999 "Towards a general approach to stereoselectively β-deuterated and 15N-labeled amino acids: synthesis of (2S,3S)-3-2H,15N]-phenylalanine” 218th National Meeting of the American Chemical Society, New Orleans, LA, MEDI 255 Derek Barnett, Ph.D.

Derek W. Barnett, Ph.D., Patent Agent

Insights