Biography
Luke is a Patent Agent within Marshall Gerstein's Chemical Sciences practice. Luke assists with the drafting and global prosecution of patents, as well as freedom to operate searches. His current work covers consumer care product and pharmaceutical spaces.
Representative Experience
- Medicinal chemistry
- Organic synthesis
- Peptides
- Antibodies
- DNA/RNA technologies
Background and Credentials
Luke achieved his Ph.D. in organic chemistry from UCLA and a B.S. in chemistry from Brandeis University. Since graduating, Luke has held postdoctoral positions at UCLA and Yale University, and as a senior research scientist at a contract research organization. Through his work, Luke has experience inventing pan-antifungal agents, writing grants and multidisciplinary research papers, and leading chemical synthesis projects for clients ranging from startups to multinational corporations.
Education
- University of California, Los Angeles (Ph.D.)
- Organic Chemistry
- Brandeis University (B.S.)
- Chemistry
Bar Admissions
Community and Professional Involvement
- AUTM
Publications and Presentations
- Molecular insights into de novo small-molecule recognition by an intron RNA structure, PNAS 2025, 122(19), e25024251221.
- Amidine-Substituted Antifungal Compounds and Methods of Use Same, Provisional Filed 2025.
- Novel Quinazoline Derivatives Inhibit Splicing of Fungal Group II Introns, ACS Chem. Biol. 2025, 20(2), 378-385.
- Antifungal Compounds and Methods of Use Same for Inhibiting Group I Intron Splicing, Provisional Filed 2024.
- Sulfane transalkylations and metal catalyzed allylic substitutions for the synthesis of composite macrobicyclic peptides, Tetrahedron Lett. 2020, 61(24), 151986.
- Syntheses of hybrid cyclopeptidyl [n]sulfanes by internal alkyl group exchange, Tetrahedron Lett. 2020, 61(24), 151985.
- Assembly of Complex Macrocycles by Incrementally Amalgamating Unprotected Peptides with a Designed Four-Armed Insert, J. Org. Chem. 2018, 83(6), 3090–3108.